- Bruker Avance III HD 400 MHz NMR Spectrometer
- NanoBay console with 2 RF channels
- SampleXpress 60-sample automation robot
- SmartProbe, capable of 1H{19F}, 19F{1H}, and X{1H} experiments, with X tunable between 109Ag and 31P (e.g., 7Li, 11B, 13C, 14N, 15N, 17O, 23Na, 29Si, 31P, 77Se, 119Sn)
- ATM (automated tune and match) module
- z-axis pulsed field gradient equipped (hardware and probe)
- Varian Unity-Inova 500 MHz NMR Spectrometer
- 3 RF channels
- Waveform generators
- z-axis pulsed field gradient equipped (hardware and all probes)
- Varian triple-resonance, inverse-detection probe, capable of 1H{13C/X} experiments, with X tunable between 15N and 31P
- Varian broadband direct detection probe (default), high band 1H and 19F, low band tunable 31P -15N
- Nalorac MBDG 3mm probe, double 13C sensitivity for small amount of samples
- Bruker MaXis Ultra-High Resolution Quadrupole Time-of-Flight MS
- Dual ion funnel design for maximal sensitivity
- Capable of resolution >65,000 FWHM for MS and MS/MS
- Mass Accuracy <1 ppm with internal calibration
- Maximum acquisition rate 20 Hz
- Bruker UltraFlex MALDI-ToF/ToF
- 2 KHz NdYAG, Smart Beam II laser capable of beam focus to 10 microns with no pixel overlap
- MALDI-MS Imaging through FlexImaging software
- Resolution of 40,000 FWHM
- Mass Accuracy <1 ppm with internal calibration
- Linear and Reflectron modes
- Thermo Orbitrap Elite with ETD-High Resolution Orbitrap MS
- Hybrid mass spectrometer with Velos linear ion trap and Orbitrap detectors
- Smaller diameter Orbitrap cell allows resolution up to 240,000 FWHM @ 400 m/z
- Mass Accuracy <1 ppm with internal calibration
- Multiple fragmentation mechanisms available, CID, HCD and ETD
- Thermo Orbitrap Q-Exactive MS
- Quadrupole-Orbitrap configuration allows broader mass range, 50-6000 m/z
- Smaller diameter Orbitrap cell allows resolution up to 140,000 FWHM @ 200 m/z
- Mass Accuracy <1 ppm with internal calibration
- Capable of fast polarity switching
- Dynamic range >5000 in 1 scan
- AB Sciex Q-Trap 5500
- Turbo ion spray source for maximal sensitivity
- Q3 linear ion trap allows traditional triple quad MRM or MSn
- Automated compound optimization facilitates method development
- Dionex UltiMate 3000 RSLC Quaternary System
- Up to 4 solvents available in one run
- Capable of pressures to 15,000 psi
- Flow 0.1 to 8.0 ml/min
- Column temperatures up to 110 Celsius
- Photodiode array UV detector
- Coupled to the Thermo Q-Exactive
- Waters Acquity UPLC System
- Capable of pressures to 15,000 psi
- Flow rates from 0.1-2.0 ml/min
- Photodiode array UV detector
- Peak widths <6 sec
- Can couple to Bruker and AB Sciex spectrometers
- Waters Nano-Acquity UPLC System
- Capable of pressures to 15,000 psi
- Splitless flow rates from 0.2-200.0 microliters/min
- Can be coupled to Bruker and Thermo instruments
Decommissioned
- IonSpec ProMALDI FT Mass Spectrometer
- Agilent 1100 HPLC-MSD VL Quadrupole Mass Spectrometer
- Agilent 1100 HPLC-MSD SL Quadrupole Mass Spectrometer – APCI Walk-up Instrument
- Agilent 1100 HPLC-MSD Ion Trap Mass Spectrometer
- Bruker Amazon Ion-Trap