(1) Spectrometers
The School of Pharmacy’s NMR facility has two NMR spectrometers: (1) a Bruker Avance III HD 400 MHz instrument (AV-400), installed in 2017, and (2) a Varian UNITY IVANOA 500 MHz instrument (UI-500), installed in 2001.
The AV-400 is equipped with a 60-sample autosampler for automated sample handling, with data acquisition controlled by IconNMR automation software. The BBO SmartProbe with automatic tunning provides excellent sensitivity for both 1H (or 19F) and 13C (or other nuclei) experiments. Users usually will run a set of pre-defined experiments on AV-400, without needs to change a lot of parameters.
The UI-500 is running VNMRJ 4.2 on a CentOS 6 linux computer. Without a robot, it is typically used in manual or semi-automated mode. User can run basic routine experiments on it like AV-400. It is also well suited for experiments which require a greater level of user interaction, such as relaxation, diffusion, kinetics and variable temperature experiments, etc. Users will have full control over all parameters.